ABSTRACT
Objective: To find out frequency of tea use with possible health effects in urban population of Hyderabad Sindh
Place and duration: At Department of Pharmacology and Therapeutics, Liaquat University of Medical and Health Sciences Jamshoro from 1[st] March 2010 to 30[th] April 2010
Study design: A cross sectional study
Methodology: The study was performed on 1432 healthy individuals. The baseline demographic characteristics were recorded on a specially designed proforma. The socioeconomic status was divided in five categories according to monthly earnings. Consumption of tea was estimated by the number of cups/day and type of tea consumed. Sugar added to tea was calculated by the number of teaspoons. Waist to hip ratio was also calculated. Persons with history of chronic diseases were excluded from the study
Results: 1102 males and 330 females participated in the study [n=1432], the mean age for men was 38+1.54 years and for women it was 30+1.25years. Among the 1102 males, 22.68% consumed 5-6 cups/day, 58.98% 3-4 cups/day and 18.33% only 2 cups/day, while females when inquired only 22% were consuming 2 cups/day with 48.48% 3-4cup/day and 31.5% were having 5-6 cups/day. Tea was prepared mostly by adding milk. 805 [73.04%] males and 250 [75.7%] females were having such tea, while only 3.62% of males 3.03% females were using black tea. The habit of having green tea was seen in 257 [23.32%] males, while none of the females in the present research was using green tea. Socioeconomically most of the participants belonged to lower socio economic group [Table - I] earning 3000-9000 rupees / month [36.47% males and 39.3% females]: Waist to hip ratio was positively correlated with the amount of sugar and frequency of tea intake
Conclusion: Tea can be hazardous for health if the pattern continues to be same, so habit of green tea ingestion should be encouraged as tea mixed with milk and sugar further adds to the burden of future diabetics
ABSTRACT
Objectives: To compare the lipid lowering affects of Atorvastatin in hypertensive dyslipidemic patients receiving Enalapril and Amlodipine
Study Design: Prospective descriptive and comparative study
Place and Duration: Study was conducted by the Department of Pharmacology LUMHS Jamshoro from 2007 to 2009 at Red Crescent Hospital Hyderabad
Methodology: One hundred essential hypertensive dyslipidemic patients were enrolled in the study. Study was approved by the ethical committee. After taking written consent patients were divided into two Groups [A and B] each group comprising of 50 patients. Atorvastatin 20 mg was combined to Group A patients at the bed time along with Enalapril 10 mg in the morning and to group B patients at the same time along with 5 mg of Amlodipine in the morning. Lipid profile was done at the base line and after 03 months [at the end of the study]
Results: At the end of the study when both groups were compared for the lipid lowering effect of Atorvastatin it was found that serum cholesterol reduced to 184.48 in group A [243.26 +/- base line] and 185.08 +/- 15.09 mg/dl in group B [240.44 +/- 31.5mg/dl base line] p value 0.78, LDL Cholesterol in group A decreased to 111.08+6.13 [243.26 +/- 22.70 at the base line] group B the LDL was decreased 104.40 +/- 4.37 which is highly significant HDL cholesterol was increased to 33.502 +/- .05 [29.90+2.65 base line] in group A, while in group B it was increased to 33.40 +/- 2.09 [29.240 at base line] triglycerides were reduced in both groups and the result were not significant. Results were compared and analyzed statistically by the SPSS version 16. Statistically the result was taken as significant. P value
Conclusion: There is significant mean change in the LDL cholesterol in group B [Atorvastatin + Amlodipine]